Design of control release drug delivery system for imaging and therapeutic applications A dissertati 2025

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A sustained release delivery system refers to a drug delivery system that can achieve a prolonged therapeutic effect by gradually releasing the therapeutic substance over an extended duration, typically days or months, following the administration of a single dose.
Controlled release are drug delivery system which maintain constant level of drug in blood and tissue for extended period of time. It implies A predictability and reproducibility in drug release kinetics In other words, the rate and duration are designed to achieve A desired concentration.
Definition of controlled-release A controlled-release drug or preparation is released into the body in specified amounts over a specified period of time. The controlled-release system is designed to release the drugs active ingredient gradually over the day.
The fundamental principle behind a controlled-release drug delivery system is to enhance the drugs biopharmaceutical, pharmacokinetic, and pharmacodynamics attributes to optimize its efficacy.
Approach to design-controlled release formulation (diffusion, dissolution ion exchange Principle) Novel Drug Delivery Systems (NDDS) aim to improve drug therapeutic efficacy and safety by ensuring the timely delivery of the drug in the required amounts to the target site.
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Controlled-release delivery devices have been developed for more than 30 years. Most of the devices utilize the fundamental principles of diffusion, dissolution, ion exchange, and osmosis (Table 22.1).
Controlled delivery is an investigative tool that helps to accomplish this objective, particularly in cases where illicit products trafficking is identified or intercepted in source or transit and then delivered under surveillance in order to identify the intended recipients.

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