Guide to IT Capital Planning and Investment Control (CPIC 2025

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CPIC is broken down into four phases. These phases are PreSelect, Select, Control and Evaluate. The Pre-Select phase is when business needs are evaluated, and where plans are developed to meet those business needs.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) is an international consortium of individual volunteers and a small dedicated staff who are interested in facilitating use of pharmacogenetic tests for patient care.
Capital Planning and Investment Control (CPIC) is a systematic approach to selecting, managing, and evaluating information technology investments. CPIC is mandated by the Clinger Cohen Act of 1996 which requires federal agencies to focus on the results produced by IT investments.
CPICs goal is to address barriers to clinical implementation of pharmacogenetic tests by creating, curating, and posting freely available, peer-reviewed, evidence-based, updatable, and detailed gene/drug clinical practice guidelines.
Capital control represents any measure taken by a government, central bank, or other regulatory body to limit the flow of foreign capital in and out of the domestic economy. These controls include taxes, tariffs, legislation, volume restrictions, and market-based forces.
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The DOE CPIC process is a structured process, which encompasses the submission of all IT investment information to the OCIO for evaluation and resultant recommendation to the Corporate Review Budget (CRB) Board for inclusion, or continued inclusion, in the Departments IT investment portfolio and budget submissions.
The CPIC process includes all stages of capital programming, including planning, budgeting, procurement, management, and assessment. Each year, as OMB produces the Presidents Budget, a team of analysts at OMB OFCIO reviews an agencies overall list of all IT investments and their detailed IT business cases.

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