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ADDITIONAL AFFECTED SIBLING FOR TRIO REQUISITION

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The document is a requisition form for the Additional Affected Sibling for Trio genetic testing by Baylor Genetics. It includes sections for patient information, insurance details, medical necessity, and consent for testing. The test aims to identify genetic changes related to medical concerns by analyzing DNA from the affected individual, their sibling, and parents. It outlines the requirements for testing, potential risks, and options for reporting results, emphasizing the importance of understanding genetic implications and the need for parental samples.

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We have answers to the most popular questions from our customers. If you can't find an answer to your question, please contact us.

Why do I only share 25% DNA with my sister?

If you have a sibling, they received their own uniquely shuffled set of chromosomes, and theres no guarantee they got the same genes from either parent that you did. You each got ~50% of each parents genes, shuffled more or less at random, and the amount of DNA you share from each parent is roughly 50%*50% or 25%.

What does a 50% DNA match mean?

For example, if you share 50% of your DNA with someone in your generation, that means you are full siblings, i.e., descended from the same parents. If you share 12.5%, that likely means you are first cousins, i.e., you share one pair of grandparents.

Why do siblings only share 50 DNA?

Trio testing is when the patients genome or exome is compared with sequences obtained from both of their biological parents. This is because if neither parent has their childs disease, it can be reasonably assumed that the variants found in the parents genomes are not the cause of their childs condition.

Why dont siblings share 100% of DNA?

The differences in genetic code between siblings are due to variations in the chromosomes passed down to them from their parents. This, more often than skeletons in the closet, also explains why some siblings will receive different ethnicity or ancestry results.

Why are you only 50% related to your siblings?

The reason there is such a wide range of variation in the percentage of shared DNA among siblings is recombination: while both of them received all their DNA from the same two people, the exact 50% they inherited from each is random.