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To prepare the solution, withdraw 15 mL of TYSABRI concentrate from the vial using a sterile needle and syringe. Inject the concentrate into 100 mL 0.9% Sodium Chloride. No other intravenous diluents may be used to prepare the TYSABRI solution. Gently invert the TYSABRI solution to mix completely.
HOW LONG CAN I STAY ON TYSABRI? You may be treated with TYSABRI for as long as you and your healthcare team decide it is right for you. In the US, more than 40% of people being treated with TYSABRI have been using it for more than 5 years.
The TOUCH Prescribing Program is designed to: Inform prescribers, infusion center healthcare providers, and patients about the risk of progressive multifocal leukoencephalopathy (PML) associated with TYSABRI including the increased risk of PML with treatment duration and prior immunosuppressant use.
by Drugs.com For people with MS, some response is noted at 12 weeks, but it may take up to 2 years for the full effects to be seen. People with Crohns disease should discontinue Tysabri if there is no benefit after 12 weeks.
Efficacy maintained over 2 years By 69% in the overall population (RR of TYSABRI/placebo was 0.31 [95% CI 0.19-0.5])
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