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IVIg is used to reduce the effects of some inflammatory conditions that involve the immune system, also known as autoimmune diseases. Its also used to increase levels of immunoglobulins if these are low, or have been lowered by treatment with other drugs, such as rituximab.
Intravenous immunoglobulin (IVIG) is a pooled antibody, and a biological agent used to manage various immunodeficiency states and a plethora of other conditions, including autoimmune, infectious, and inflammatory states. The ultimate goal of this therapy is to normalize a compromised immune system.
While IVIG causes a rapid rise in serum IG, SCIG does not. IVIG also has more side effects than SCIG. IVIG is given into a vein (intravenously) as an infusion that can usually take from 1 to 4 hours or even longer, depending on the dose and other factors involving the patients health.
One reason you might need IVIG is if your body does not make enough antibodies. This is called humoral immunodeficiency. The IVIG simply provides extra antibodies that your body cannot make on its own.
IVIG is used to treat various autoimmune, infectious, and idiopathic diseases. IVIG is an approved treatment for multifocal motor neuropathy, chronic lymphocytic lymphoma, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease and ITP.

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Depending on a persons condition, they may need infusions throughout their life. IVIg is generally safe, and any side effects are usually not serious. However, in rare cases, IVIg can cause complications up to 72 hours after the procedure, such as blood clots or an anaphylactic reaction.

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