Guide to the preparation, use and quality assurance of 2026

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The legal framework defining the quality and safety standards for blood and its components is set out in Directive 2002/98/ECEN, also referred to as the European Blood Directive. It covers all steps in the transfusion process from donation, collection, testing, processing, and storage to distribution.
Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients.
The patient should not be transfused purely because compatible blood is available. Effective transfusion requires a minimum of 2 units of blood for an adult or 20ml whole blood (10-15ml packed cells) per kilogram body weight for a child.

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The Guide to the preparation, use and quality assurance of blood components (the Blood Guide) is a compendium of widely accepted, harmonised, European standards that provide safety, efficacy and quality requirements for the preparation, use and quality control of blood components in Europe and beyond.
The blood should be kept in blood bank refrigerator at 4-6C 2C. The temperature of the blood should be monitored continuously.
All blood components should be administered using a blood administration set with an integral mesh filter (170-200 micron). Transfusion should be completed within 4 hours of leaving temperature-controlled storage.
One cycle consists of-one ECV whole blood collection in kit bowl, centrifugation of bowl to separate components, collection of required component (platelets) in collection bag and finally return other constituents like red cells, leucocytes and plasma to donor. This cycle is repeated till therapeutic dose is attained.
One cycle consists of-one ECV whole blood collection in kit bowl, centrifugation of bowl to separate components, collection of required component (platelets) in collection bag and finally return other constituents like red cells, leucocytes and plasma to donor. This cycle is repeated till therapeutic dose is attained.

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