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- In the 'Material' section, select the type of specimen you are submitting. Options include blood samples, dried blood spot cards, or DNA. Ensure you provide the required quantities.
- Complete the 'Declaration of Consent' by reviewing and signing to confirm understanding of genetic testing implications. This is crucial for data protection compliance.
- Fill in the 'Indication' section with details about suspected diagnosis and major clinical symptoms. Include any preliminary genetic diagnostics if available.
- Provide family medical history in the 'Pedigree' section, indicating any relatives affected by similar conditions.
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What is an example of germline cancer?
Germline BRCA1/2 mutations are known to be directly associated with increased risks in multiple cancer types including and ovarian cancers (1315).
What are the hereditary tumor syndromes?
Most hereditary cancer syndromes exhibit autosomal dominant inheritance. The most common hereditary cancer syndromes related to womens cancer include hereditary and ovarian cancer syndrome, Lynch syndrome, LiFraumeni syndrome, Cowden syndrome, PeutzJeghers syndrome, and hereditary diffuse gastric cancer.
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