Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument 2026

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  1. Click ‘Get Form’ to open it in the editor.
  2. Begin with Section 1, where you will assess your general health. Circle the number that best represents your current health status.
  3. Proceed to Section 2, comparing your health to one year ago. Again, circle the appropriate number based on your experience.
  4. In Sections 3-12, evaluate how much your health limits various daily activities. For each activity listed, circle '1', '2', or '3' based on the level of limitation.
  5. Continue through Sections 13-19, focusing on how physical and emotional problems have affected your work and daily activities. Circle 'YES' or 'NO' for each question.
  6. Complete the remaining sections by circling numbers that reflect your feelings and experiences over the past four weeks regarding pain, social activities, cognitive function, and overall quality of life.

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The MSQOL-54 is a multidimensional health-related quality of life measure that combines both generic and MS-specific items into a single instrument.

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