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312.66 Assurance of IRB review. An investigator shall assure that an IRB that complies with the requirements set forth in part 56 will be responsible for the initial and continuing review and approval of the proposed clinical study.
The basic principle of human subjects protection is that people should not (in most cases) be involved in research without their informed consent, and that subjects should not incur an increased risk of harm from their involvement in research, beyond the normal risks inherent in everyday life.
The Certified IRB Professional (CIP) credential constitutes formal recognition of an IRB professionals broad knowledge of IRB functions and expertise about HRPPs. It signals that its holders are highly qualified to discharge their duties pursuant to United States rules and regulations, prevailing ethical codes.
All research staff on an IRB protocol must have an updated CITI training certificate (within the last three years) filed within Mentor IRB/PI Documentation and researchers are responsible for ensuring their CITI training does not lapse. CITI trainings will automatically expire at the 3 year mark.
Institutional review boards (IRBs) have the federally mandated responsibility to review research involving human subjects to ensure that a proposed protocol meets the appropriate ethical guidelines before subjects may be enrolled in the study.
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