Mycotoxin risk assessment 2025

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Many clays are effective in binding mycotoxins, including smectite, montmorillonite (MMT), bentonite, and sepiolite. The smectite is one of the largest classes of phyllosilicate groups that contains MMT known for its high adsorption capacity.
Aflatoxin, ochratoxin A (OTA), fumonisins, trichothecenes, and zearalenone toxins are the most important mycotoxins related to agriculture, economics, and public health [10], [11], [12].
Aflatoxin B1, the most toxic, is a potent carcinogen and has been directly correlated to adverse health effects, such as liver cancer, in many animal species. Aflatoxins are largely associated with commodities produced in the tropics and subtropics, such as cotton, peanuts, spices, pistachios, and maize.
The Health and Safety Executives Five steps to risk assessment. Step 1: Identify the hazards. Step 2: Decide who might be harmed and how. Step 3: Evaluate the risks and decide on precautions. Step 4: Record your findings and implement them. Step 5: Review your risk assessment and update if. necessary.
The standard confirmatory methods include high performance liquid chromatography (HPLC) with various detection methods such as fluorescence or mass spectrometric (LCMS or LC-MS/MS); and gas chromatography for a few select mycotoxins. Other analytical methods are available but much less common.
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The acute symptoms in animals include liver, spleen and kidney damage and toxicity to the immune system. For humans, nausea, gastrointestinal disturbances and vomiting have been reported. Patulin is considered to be genotoxic however a carcinogenic potential has not been demonstrated yet.
While over 300 mycotoxins have been identified, six (aflatoxins, trichothecenes, zearalenone, fumonisins, ochratoxins, and patulin) are regularly found in food, posing unpredictable and ongoing food safety problems worldwide.
The FDA has a monitoring program to help ensure that the foods available for you to buy are not contaminated with mycotoxins. The mycotoxins in human food that the FDA currently focuses on are aflatoxins, deoxynivalenol, fumonisins, patulin, ochratoxin A, T-2 and HT-2 toxins, and zearalenone.

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