Pico worksheet and search strategy 2025

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PICO is widely used in evidence-based healthcare to formulate questions and to develop search strategies. Cochranes PICO search helps you find Cochrane Reviews by specifying any of four potential components of a healthcare question: Population (or Patient or Problem)
Before you start your search, it is important to have a well-built question. One way to construct a well-built question is to use the PICO model. PICO stands for patient/population, intervention, comparison and outcomes.
Tips for a Successful PICO Search Strategy Use Boolean operators (AND, OR, NOT) to combine search terms and tailor your search to the research question at hand. Include synonyms or related terms for key concepts to broaden your search while maintaining relevance (e.g., medication, drug, pharmaceutical).
A PICO worksheet helps you organize your search strategy. Use a worksheet to: Structure your question using the PICO elements. Jot down terms that describe each element of the question, i.e. plain language terms, alternate terms (synonyms), and subject headings.
Using PICO to Frame Clinical Questions P = Patient or Problem. How would you describe the patient? I = Intervention. What would you like to do to help the patient? C = Comparison. What would be the alternative to the intervention you selected? O = Outcome. By doing the intervention, what do you hope to accomplish?
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