Urinalysis (UA) and the Diagnosis of UTIs 2025

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Prompt and accurate diagnosis of uncomplicated UTIs is crucial for timely and appropriate management. Diagnosis relies on clinical history, urinalysis, and culture, with proper specimen collection being essential.
In symptomatic patients, a colony count as low as 100 CFU per mL suggests UTI, and antibiotics should be considered. The presence of bacteria in a properly collected male specimen is suggestive of infection, and a culture should be obtained.
A healthcare provider may order the following tests to diagnose a UTI: Urinalysis. During this test, youll pee into a special cup. The provider will send the sample to a laboratory, where technicians will examine it for signs of a UTI using multiple variables such as nitrites, leukocyte esterase and white blood cells.
A high level of leukocytes is usually a sign of inflammation associated with an infection. A urinalysis can also detect nitrites produced by gram-negative bacteria such as Escherichia coli (E. coli), which is the most common cause of UTIs.
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