ASAM-Chicago-10-2-04 indd - buprenorphine samhsa 2025

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Generally, initiation should occur at least 612 hours after the last use of or other short-acting opioids, or 2472 hours after their last use of long-acting opioids such as methadone. Induction of should start with a dose of 24 mg. Dosages may be increased in increments of 24 mg.
dosages typically range from 4 mg to 16 mg per day. The maximum daily dose is 24 mg, but higher dosages are associated with more risks, including a greater risk for side effects and misuse.
Filling Prescriptions Physicians prescribing products are required to include both the DEA number and the special X DEA registration number on any prescription for .
The three-day rule permits practitioners to administer no more than one days medication at a time for a maximum of three days, which cannot be renewed or extended. During the three-day period, the provider is expected to arrange for the patients referral for treatment in a maintenance or detoxification program.
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