Functional Genomics of Critical Illness and Injury - National Institutes 2025

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Functional genomics is defined as the use of genome data to study genome-wide gene and protein expression and their functions. For that, high-throughput methods are used to understand gene transcription and translation and proteinprotein interaction (PPI) better.
Structural genomics involves the physical nature of genomes and includes the sequencing and mapping of genomes. Functional genomics involves studying the expression and function of the genome. Genomics can also involve the investigation of interactions between genes and between genes and the environment.
Answer: Functional genomics focuses on understanding gene function, interaction, and regulation within a single organism, while comparative genomics investigates the similarities and differences in genomes between different organisms.
The Oxford Brookes Centre for Functional Genomics provides specialist support for DNA and RNA sequencing workflows including short courses and training opportunities in cutting-edge methods for sequencing data analysis.
These various efforts have led to the emergence of multiple fields within the area of genomics, including the following: Structural genomics. Studies the entire genome to determine the structure of every protein encoded by the genome. Functional genomics.
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