Blastocyst Formation - theology mercer 2025

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Is 4aa or 5aa Better? Although both embryo grades are considered excellent with a 65% pregnancy rate and 50% live birth rate, 5aa is considered better because the blastocyst is partially or completely free from the zona pellucida and further along than an expanded blastocyst.
Male embryos develop quicker in the early stages, which is why theres such a drastic difference between the two. Gender selection is nearly impossible at this stage then. I personally managed to get a girl (4AA) and a boy (5AA), so anything is possible!
The Gardner blastocyst grading system assigns 3 separate quality scores to each blastocyst embryo: ICM gradeInner cell mass quality A Many cells, tightly packed B Several cells, loosely grouped C Very few cells
If we were to look at them both under a microscope, the only difference we would see is that the 4AA embryo is still in its shell, whereas the 5AA is showing signs of hatching (in non-PGT cases). In PGT cases, a 4AA and 5AA are both considered hatching blastocysts, with the latter simply being more expanded.
Morula. The morula is observed on day 4 and is formed after the compaction and fusion of blastomeres of the dividing embryos. As the morula continues to develop, fluid starts to accumulate forming a cavity, the blastocoel, giving rise to the blastocyst.

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The cell of the zygote continuously divides, eventually forming a hollow ball of cells called the blastocyst. The blastocyst stays in their for several days before it implants in the inner lining of their uterine wall (endometrium). It continues to make new cells, which separate into layers.
Based on this system, a high quality embryo could have a grade of 4AA or 5AA, but embryos with lower scores are still capable of implanting and growing into a healthy baby.
Gardner Blastocyst Grading System Embryo GradePregnancy RateLive Birth Rate 3AA, 4AA, 5AA 65% 50% 3AB, 4AB, 5AB 55% 40% 3BB, 4BB, 5BB 30% 20% 4BC, 5BC, 6BC 10% 5%

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