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Begin by reviewing the introduction section, which outlines the significance of hippocampal CA1 pyramidal cells and their functional distinctions. This will provide context for your responses.
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In the results section, summarize key findings regarding firing rates and phase preferences of deep versus superficial neurons. Use bullet points for clarity.
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Fill out Hippocampal CA1 pyramidal cells form functionally distinct sublayers Nature Neuroscience, (2011) doi online It's free
In the hippocampus, pyramidal cells in CA1 and the subiculum process sensory and motor cues to form a cognitive map encoding spatial, contextual, and emotional information, which they transmit throughout the brain.
What are two key brain structures involved in depression?
The main subcortical limbic brain regions implicated in depression are the amygdala, hippocampus, and the dorsomedial thalamus. Both structural and functional abnormalities in these areas have been found in depression.
What is the CA1 sub region of the hippocampus?
The CA1 region plays a role in input integration, and the subiculum contributes to memory retrieval (Small, Schobel, Buxton, Witter, Barnes, 2011). In addition to its role in learning and memory, the hippocampal formation has been implicated in other functions.
What is hippocampal long-term depression?
Long-term depression (LTD) is a lasting decrease in synaptic effectiveness that follows some types of electrical stimulation in the hippocampus.
What is the function of the hippocampus CA1 CA3?
In conclusion, the present experiments demonstrate that both hippocampal areas CA1 and CA3 contribute to the context dependence of extinguished fear. CA1 and CA3 are both required for contextual encoding of extinction, whereas area CA1 is essential for context-dependent retrieval.
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People also ask
What are the two distinct forms of long term depression coexist in CA1 hippocampal pyramidal cells?
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors (NMDARs) and the other dependent on the activation of metabotropic glutamate receptors (mGluRs), are shown to coexist in CA1 hippocampal pyramidal cells of juvenile (1135 day-old) rats.
Related links
Hippocampal CA1 pyramidal cells form functionally distinct
by K Mizuseki 2011 Cited by 522 Hippocampal CA1 pyramidal cells form functionally distinct sublayers. Nat Neurosci. 2011 Aug 7;14(9):1174-81. doi: 10.1038/nn.2894. Authors.
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