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"APPLICATION OF MULTIOBJECTIVE OPTIMIZATION TO DETERMINING AN

"APPLICATION OF MULTIOBJECTIVE OPTIMIZATION TO DETERMINING AN 2025

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The document presents a master's thesis by Douglas C. McConahy on the application of multiobjective optimization to determine optimal pump speeds for Left Ventricular Assist Devices (LVADs). It discusses the importance of selecting appropriate pump speeds to ensure adequate cardiac output while maintaining safe physiological parameters such as left atrial pressure and arterial pressure. The research formulates the pump speed selection problem as a multiobjective optimization issue, introduces penalty functions for hemodynamic variables, and identifies a noninferior set of pump speeds. A decision support system is developed to assist clinicians in selecting an optimal speed based on varying patient conditions and preferences.

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