Agency Announcements, Small Business Innovation Research topics, Small 2025

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The NIH releases a Contract solicitation once per year. See more information here.
An SBIR award gives flexibility in partnering with subcontractors and allows up to 33% of the funding to be used for partners. An STTR award requires that 40% of the funding goes to a research institution, 30% goes to the small business applicant and 30% is discretionary.
Also, the budget supplied with the grant application is very tight with very little room for funds to be allocated to unforeseen costs that will inevitably pop up for any startup taking on a high technology development project. Clearly, a company cannot commercialize a high tech product on SBIR grant funding alone.
Together, these programs are known as Americas Seed Fund. The SBIR and STTR programs are one of the largest sources of early-stage capital for technology commercialization in the United States.
Can a small business switch between the Small Business Innovation Research (SBIR) program or the Small Business Technology Transfer Research (STTR) programs after receiving Phase I funding? Yes.
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The SBIR program encourages U.S. small businesses with fewer than 500 employees to provide quality research and to develop new processes, products and technologies in support of the missions of the U.S. government.

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