Part 8 PDF - 2946 KB - Centers for Disease Control and Prevention - cdc-2025

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The recommended treatment for gonorrhea is ceftriaxone monotherapy given intramuscularly, with dosing based on the patients body weight. For chlamydia, doxycycline is the preferred treatment. A test-of-cure is recommended for all cases of pharyngeal gonorrhea and for chlamydia if treated with azithromycin.
Treatment for uncomplicated urogenital chlamydia infection is with azithromycin. Doxycycline is an alternative, but azithromycin is preferred as it is a single-dose therapy.
Both the Worldwide Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) recommend either azithromycin or doxycycline as first-line treatments for chlamydia. Though both are effective, the CDC notes that doxycycline may be slightly more effective.
CDCs National Center for Injury Prevention and Control (NCIPC) works to prevent injuries and violence, and reduce their consequences.
Recommended Regimens for Chlamydial Infection Among Adolescents and Adults. Doxycycline 100 mg orally 2 times/day for 7 days. Recommended Regimen for Chlamydial Infection During Pregnancy. Azithromycin 1 g orally in a single dose. Recommended Regimen for Chlamydial Pneumonia Among Infants.
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Key Vaccine19-26 years50-64 years COVID-19 At least 1 dose of the current COVID-19 vaccine Influenza/Flu Every Year RSV If pregnant during RSV season If aged 60 through 74 years Tdap/Td Tdap every pregnancy. Td/Tdap every 10 years for all adults.10 more rows Nov 21, 2024
The Centers for Disease Control and Prevention (CDC) collaborates to create the expertise, information, and tools that people and communities need to protect their health through health promotion, prevention of disease, injury and disability, and preparedness for new health threats.
However, in July 2021, due to growing evidence of inferiority of single-dose azithromycin for extragenital infections,4 the CDC updated chlamydia treatment guidelines recommending the multidose doxycycline (100 mg twice daily for 7 days) as the preferred regimen and classifying azithromycin as an alternative.

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