Patient information about Crohns disease and Humira 2025

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There are no known interactions between Humira (adalimumab) and food. Most patients should be able to safely follow their normal eating and drinking habits while taking Humira.
How does HUMIRA work? The protein TNF-alpha is believed to be part of your bodys natural processes involved in creating inflammation, and in some cases, excess inflammation. When used as prescribed, HUMIRA targets and blocks TNF-alpha, which can help reduce the excess inflammation associated with Crohns disease.
Research from 2017 also found that Humira successfully treated about two-thirds of patients with Crohns and that more than half remained free of surgery 4 years after they began treatment. A 2019 study reported that Humira improved patients outcomes and remission rates for 6 years.
The most common side effect of Humira are injection site reactions; they may affect up to 37% of people receiving the medication. If this happens to you, youll likely notice some skin redness or irritation near where Humira was injected. Swelling and pain are also possible.
Humira is in a class of medications called tumor necrosis factor (TNF) blockers or inhibitors. It works by attaching to TNF-alpha and blocking the protein from attaching to its receptor, preventing it from attacking healthy cells and causing an inflammatory response.
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The gastrointestinal tract can frequently show a reaction to the drug. Among others, diarrhea, abdominal pain, nausea and gastrointestinal bleeding have been reported.

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