Migraine Action Plan 2025

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Triptans reverse this process. These headache tablets relieve the throbbing pain by constricting and releasing blood vessels in the brain. There are several triptans, including Zolmitriptan and Sumatriptan. Sumatriptan 100 mg is the strongest migraine medicine.
Acetaminophen and nonsteroidal anti-inflammatory drugs are first-line treatments for mild to moderate migraines, whereas triptans are first-line treatments for moderate to severe migraines. Although triptans are effective, they may be expensive.
A migraine cocktail is also available in OTC medication. OTC products usually contain aspirin, acetaminophen, and caffeine. These components are more effective when theyre used together than when theyre taken alone.
Stay hydrated. Dehydration can cause a regular headache, and many people say that it can trigger a migraine, as well. Try to regularly drink about 64 ounces of water a day.
Use NSAIDs (including aspirin), nonopioid analgesics, acetaminophen, or caffeinated analgesic combinations for mild‐to‐moderate attacks and migraine‐specific agents (triptans, dihydroergotamine) for moderate or severe attacks and mild‐to‐moderate attacks that respond poorly to NSAIDs or caffeinated combinations.
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In other words there is more to diet and migraine than simply excluding the 5 Cs (cheese, chocolate, coffee, coke, and citrus fruits). They performed double blind challenges in a selection of their cases; these were confirmatory of the results of open challenge in the majority of cases.

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