Molecular diagnostic Laboratory Cancer and Endocrine Next Generation Sequencing Requisition form 2025

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NGS can sequence hundreds and thousands of genes or whole genome in a short period of time. The sequence variants/mutations detected by NGS have been widely used for disease diagnosis, prognosis, therapeutic decision, and follow up of patients.
Detailed analysis of the patients tumor DNA and RNA that provides comprehensive insights in one test to what treatments may work best. Is more cost-effective to start with than traditional diagnostic work-ups like IHC, FISH, flow cytometry, morphology and cytogenetics.
NGS enables the interrogation of hundreds to thousands of genes at one time in multiple samples, as well as discovery and analysis of different types of genomic features in a single sequencing run, from single nucleotide variants (SNVs), to copy number and structural variants, and even RNA fusions.
The technology is used to determine the order of nucleotides in entire genomes or targeted regions of DNA or RNA. NGS has revolutionized the biological sciences, allowing labs to perform a wide variety of applications and study biological systems at a level never before possible.
NGS applications can be used in the diagnosis of infectious diseases. (A) Microbes grown from patient samples provide microbial DNA for WGS in which millions of fragments are read in parallel and assembled to reconstruct the microbial genome.
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NGS provides a good solution for detecting rare variations. Because it allows testing of multiple genes at once, NGS greatly improves the variation detection rate. Many patients with hereditary cancer have tested negative for genetic variations, but with NGS, it is easier to find causative mutations.

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