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All patients diagnosed with BIA-ALCL requires implant removal and en bloc capsulectomy. In the presence of suspicious enlarged lymph nodes, surgical lymphadenectomy and bone marrow biopsy should be performed, with implant removal and en-bloc capsulectomy, to assess disease dissemination.
A diagnosis of ALCL requires taking a biopsy (small sample of tumor tissue or abnormal skin tissue) and looking at the cells under a microscope. Additional tests may be conducted to give physicians more information about the disease and how far it has spread in the body.
A: There is no blood test to specifically screen for BIA-ALCL.
By contrast, ing to the most recent figures reported by the FDA [20], BIA-ALCL carries a risk of mortality of about 5%.
Half of all cases of BIA-ALCL reported to the FDA have been diagnosed within seven to eight years after implant surgery, though the American Society of Plastic Surgeons (ASPS) notes that symptoms can appear two to 28 years after the procedure.
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ALCL usually responds well to chemotherapy, and treatment may make it disappear. This is called remission. There is a risk that the lymphoma may come back in the future.
The main symptoms of BIA-ALCL are persistent swelling, presence of a mass or pain in the area of the breast implant. These symptoms may occur well after the surgical incision has healed, often years after implant placement.
Research has shown that 93% of people diagnosed with BIA-ALCL are still disease-free three years after treatment. Some people whove been treated for BIA-ALCL decide to have breast reconstruction surgery with smooth implants, flaps (autologous reconstruction), or fat grafting.