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#2. Are there different types of CLIA certificates? Certificate for Provider-performed Microscopy (PPM) procedures: Certificate of Compliance (COC): Certificate of Accreditation (COA): Certificate of Registration: Certificate of Waiver (COW):
The Clinical Laboratory Improvement Amendments (CLIA) of 1988 (42 USC 263a) and the associated regulations (42 CFR 493) provide the authority for certification and oversight of clinical laboratories and laboratory testing.
Types of CLIA Certificates Certificate of Waiver. Certificate for Provider Performed Microscopy Procedures (PPM) Certificate of Registration. Certificate of Compliance. Certificate of Accreditation.
Clinical Laboratory Improvement Amendments (CLIA)
The Centers for Medicare Medicaid Services (CMS) regulates all laboratory testing (except research) performed on humans in the U.S. through the Clinical Laboratory Improvement Amendments (CLIA). In total, CLIA covers approximately 320,000 laboratory entities.
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As defined by CLIA, waived tests are simple laboratory examinations and procedures that have an indocHub risk of an erroneous result. Examples of waived tests include: dipstick urinalysis, fecal occult blood, urine pregnancy tests, and blood glucose monitoring.
What is a CLIA Categorization? The FDA categorizes clinical laboratory tests by their complexityfrom the least to the most complex: waived tests, moderate complexity tests, and high complexity tests.
Clinical Laboratory Improvement Amendments defines 4 categories for laboratory testing in ascending order of complexity: waived, PPM, moderate complexity, and high complexity.

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