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SARS-CoV-2 variant of interest BA.2.86, with the earliest sample collected in July 2023, has 36 amino acid substitutions relative to XBB.1.5, including in key antigenic sites in the spike protein.
Newer versions of COVID-19, like the Omicron strain EG.5, tend to infect the upper respiratory tract. Common symptoms of the new COVID-19 variants include a runny nose, sore throat, and other symptoms similar to a cold.
Many people who are infected have more mild symptoms like a scratchy throat, stuffy or runny nose, occasional mild cough, fatigue, and no fever. Some people have no symptoms at all, but they can still spread the disease. Fever seems to be one of the more common early markers of COVID-19, Kline noted.
On June 30, the Centers for Disease Control and Prevention added three symptoms to its COVID-19 list: Congestion/stuffy nose, nausea and diarrhea. Those three new conditions now join other symptoms identified by the CDC: Fever. Cough.
CDC Centers for Disease Control and Prevention.
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Finally, in October 1992, Congress changed CDCs official name to the Centers for Disease Control and Prevention, to recognize CDCs leadership role in prevention. Today, CDC is both the nations prevention agency and a global leader in public health.
On 5 May 2023, more than three years into the pandemic, the WHO Emergency Committee on COVID-19 recommended to the Director-General, who accepted the recommendation, that given the disease was by now well established and ongoing, it no longer fit the definition of a PHEIC.
COVID-19 symptoms and what to do feeling tired or exhausted. an aching body. a headache. a sore throat. a blocked or runny nose. loss of appetite. diarrhoea. feeling sick or being sick.

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