PHQ-4: Validated Screening Tool for Anxiety and Depression 2025

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Its purpose is to allow for ultra brief and accurate measurement of core symptoms/signs of depression and anxiety by combining the two-item measure (PHQ2), consisting of core criteria for depression, as well as a two-item measure for anxiety (GAD2), both of which have independently been shown to be good brief
Although designed as a screening tool for generalized anxiety, the GAD-7 is also performs reasonably well as a screening tool for three other common anxiety disordersPanic Disorder, Social Anxiety Disorder, and Posttraumatic Stress Disorder.
The PHQ-4 is a reliable and valid instrument for screening depressive and anxiety symptoms, both for the clinical and nonclinical populations. Due to the brevity of its administration, the PHQ-4 could be a clinical tool that contributes to optimizing health resources.
PHQ-4 combines two screening questions for depression (PHQ-2) and two screening questions for anxiety (the two-item Generalized Anxiety Disorder Scale, GAD-2; Kroenke et al., 2009). PHQ-2 was derived from PHQ-9, asking about depressed mood and loss of interest, two core symptoms of depression (Kroenke et al., 2003).
The PHQ-2 includes the first two items of the PHQ-9. The purpose of the PHQ-2 is to screen for depression in a first-step approach. Patients who screen positive should be further evaluated with the PHQ-9 to determine whether they meet criteria for a depressive disorder.
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Score Depression Severity Action 0 - 4 None-minimal Patient may not need depression treatment. 5 - 9 Mild Use clinical judgment about treatment, based on patients duration of symptoms and functional impairment.
The PHQ 2 scoring options for how often theyve experienced the indicated symptoms are: Not at all (=0) Several days (=1) More than half the days (=2) Nearly every day (=3)

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