Pico worksheet sample 2025

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One way to construct a well-built question is to use the PICO model. PICO stands for patient/population, intervention, comparison and outcomes. Who is your patient? What do you plan on doing for the patient?
PICO(T): Framing the Research Question Example: You decided to research the chickenpox vaccine and risk involved with the vaccine. The PICO question format might be: What are the adverse effects in infants who receive the chickenpox vaccine?
A PICO worksheet helps you organize your search strategy. Use a worksheet to: Structure your question using the PICO elements. Jot down terms that describe each element of the question, i.e. plain language terms, alternate terms (synonyms), and subject headings.
Using PICO to Frame Clinical Questions P = Patient or Problem. How would you describe the patient? I = Intervention. What would you like to do to help the patient? C = Comparison. What would be the alternative to the intervention you selected? O = Outcome. By doing the intervention, what do you hope to accomplish?
The PICO tool, by design, urges researchers to channel their focus towards specific elements: population, intervention, comparison, and outcome. PICO mostly focuses on intervention (or therapy) clinical questions.
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