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Buprenorphine, which is a Schedule III medication, can be prescribed by means of telehealth, so long as the prescription adheres to all relevant federal, state, and local laws; regulations; and other related requirements. Under the COVID-19 public health emergency (PHE), telehealth prescribing was expanded.
In October 2002, the Food and Drug Administration (FDA) approved two buprenorphine products (Suboxone and Subutex)1 for the treatment of narcotic addiction. Both products are high dose (2 mg and 8 mg) sublingual (under the tongue) tablets.
Buprenorphine is an opioid partial agonist. This means that, like opioids, it produces effects such as euphoria or respiratory depression. With buprenorphine, however, these effects are weaker than those of full drugs such as and methadone.
Buprenorphine hydrochloride sublingual tablets marketed under the trade name Subutex and buprenorphine hydrochloride/naloxone hydrochloride sublingual tablets and sublingual film marketed under the trade name Suboxone are covered under the Subutex and Suboxone REMS programs.
Physicians, physician assistants, and nurse practitioners who have a current Drug Enforcement Administration (DEA) registration with authority to prescribe controlled substances can prescribe buprenorphine for OUD , though some states may have additional requirements to do so.
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On March 16, 2020, DEA permitted controlled substances, including buprenorphine, to be prescribed via telemedicine (defined as a two-way audio-visual connection) without a prior in-person visit.
Buprenorphine is a mu opioid receptor partial agonist, kappa opioid receptor antagonist. Its activity in opioid maintenance treatment is attributed to its slow dissociation from the mu receptors in the brain which reduces craving for opioids and opioid withdrawal symptoms.
BRIXADI (buprenorphine) extended-release injection for subcutaneous use contains a medicine called buprenorphine. Buprenorphine is an opioid that can cause serious and life-threatening breathing problems, especially if you take or use certain other medicines or drugs. Talk to your healthcare provider about naloxone.

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