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The drug reduces how much inflammation is seen on your MRI scans. Doctors can see this inflammation as lesions, areas of damage to nerves. You inject ofatumumab under your skin with an injector pen once every four weeks.
You may have to adapt your daily life if youre diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
In 2 studies vs AUBAGIO (teriflunomide), KESIMPTA was proven superior at reducing the rate of relapses and active lesions, and slowing disability progression.
In patients with multiple sclerosis (MS) fatigue is the most common symptom and one of the most disabling features. As many as 40% have described it as the single most disabling symptom--a higher percentage than weakness, spasticity, motor problems, or bowel or bladder problems.
According to the National Multiple Sclerosis Society, approximately 40% of people with MS in the United States receive disability benefits. 15 MS is a progressive disease. Its likely that many of them continued to be able to work with MS for many years before they needed to apply for disability.
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Kesimpta is a monoclonal antibody that binds to a docking site (CD20) on some immune B cells and depletes them. B cells are among immune cells that have been implicated in causing nervous system damage in MS.
MS can weaken the muscles that control the lungs. Such respiratory issues are the major cause of sickness and death in people in the final stages of MS. Spasticity or an increase in stiffness and resistance as a muscle is moved can impair movement and cause pain and other problems.
KESIMPTA works by impacting your immune system, so it could increase the risk of getting serious infections, including: Hepatitis B virus (HBV) reactivation: Before starting KESIMPTA, youll get a blood test for HBV. If youve ever had HBV infection, it may become active again during or after treatment with KESIMPTA.
All participants in the study who were vaccinated during continuous Kesimpta treatment developed an immune response as soon as one week after initial vaccination. Immune response in participants who received a booster during treatment was similar to those who received a booster before treatment.
Most patients and physicians harbor an unfounded view of MS as a relentlessly progressive, inevitably disabling disease. The truth is that 15 years after the onset of MS, only about 20% of patients are bedridden or institutionalized.

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