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Abstract. The origin of rheumatoid arthritis (RA) is in our opinion a bacterial infection. The infection gives rise to changes in the macrophages, with release of enzymes, etc., and secondarily abnormal immune processes occur.
2:10 28:38 Start by looking at the skin of the dorsum of the hands using the mnemonic ears. Then look at theMoreStart by looking at the skin of the dorsum of the hands using the mnemonic ears. Then look at the palms. Next look at the joints for swelling and deformities.
Some of the main blood tests used include: erythrocyte sedimentation rate (ESR) which can help assess levels of inflammation in the body. C-reactive protein (CRP) another test that can help measure inflammation levels.
History of Present Illness Date of onset and type of onset (suddenly or slowly). Location of pain: (joints, muscles, soft tissues) Presence of swelling* (before and now) Subsequent course (progressive, intermittent or remittent). Present status (better, same or worse). Impact on their lives.
There is no one blood test or physical finding to confirm the diagnosis. During the physical exam, your doctor will check your joints for swelling, redness and warmth. He or she may also check your reflexes and muscle strength.
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Gently palpate bones, joints, muscles, and surrounding tissue for heat, swelling, stiffness, tenderness, or crepitation. Ask the patient to move major joints (knees, shoulders, hips, and ankles) through the expected ROM movements. Observe the quality and equality of motion bilaterally with the same body parts.
Imaging Tests Magnetic resonance imaging (MRI) and ultrasound may help diagnose rheumatoid arthritis in the early stages of the disease. In addition, these imaging tests can help evaluate the amount of damage in the joints and the severity of the disease.
BLOOD TESTS: Complete Blood Count (CBC): includes white blood cell count, hematocrit, and platelets. Creatinine (Cr): measures kidney function. Liver Function Tests (ALT/AST): measures liver function; can be elevated due to medication toxicity.
In the 1950s, corticosteroids were introduced for the treatment of RA. Prior to this, treatment of RA was largely limited to non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin. While these classes of drugs reduce inflammation and provide symptomatic relief, they do not slow disease progression.
The first visit will include a physical exam in which your rheumatologist will search for joint swelling or nodules that may indicate inflammation, says Dr. Smith. Lab tests, such as X-rays and blood work, may also supply pieces of the puzzle to assist your rheumatologist in arriving at your diagnosis.

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