Amniotic Fluid Embolism 2025

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AFE is rare. It affects 1 in every 40,000 deliveries in the United States and 1 in every 53,800 deliveries in Europe. The symptoms of AFE are similar to other complications during childbirth, like uterine rupture, placental abruption and eclampsia.
Causes and risk factors Alternately, an amniotic fluid embolism may occur due to a tear in the amniotic sac, leading to the leaking fluid entering the mothers bloodstream. Another possible cause could be the death of the fetus, causing a breakup of tissue which then enters into the bloodstream.
AFE occurs when amniotic fluid which surrounds the fetus in the enters the mothers bloodstream and triggers a severe allergic reaction that can lead to cardiovascular collapse. It has a mortality rate of 60% to 80%, with half of mothers dying within the first hour along with a 30% risk of fetal death.
Admit the patient with amniotic fluid embolism (AFE) into the intensive care unit (ICU). Treatment is supportive and includes the following: Administer oxygen to maintain normal saturation. Intubate if necessary.
Worldwide, the estimated incidence of AFE ranges from 1 in 15,200 to 1 in 53,800 deliveries [2]. It has been deemed a leading cause of maternal mortality, with a fatality rate ranging from 11 to 43 % [3].
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