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Infection of the knee joint following ACL reconstruction is a rare but serious complication. Past studies have attempted to uncover the risk factors that make certain individuals more susceptible to infection than others. But many of these studies have been limited to small and medium-sized cohorts. A new study reported in the American Journal of Sports Medicine has examined the largest, single-center cohort to date. Findings reveal that graft type, age, and revision surgery could be linked to the risk of infection following ACL reconstruction. The researchers behind the study reviewed more than 11,000 total procedures performed at a single institution between 2010 and 2018. Among these, 48 infections were identified. In addition to infections, the researchers reviewed patient and procedure characteristics associated with infection, infection characteristics, incidence of ACL graft retention and factors associated with retention versus removal of ACL grafts. A regression analysis d