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This is a rare autosomal recessive disorder and 20% of CIPA patients do not survive past 3 years of age. Insensitivity to pain usually makes it harder to locate source of infection and leads to delayed diagnosis and treatment.
How long do CIPA patients live?
CIPA is extremely dangerous, and in most cases the patient doesnt live over age of 25. Although some of them can live a fairly normal life, they must constantly check for cuts, bruises, self-mutilations, and other possible unfelt injuries.
How long can CIPA patients live?
There are few cases of insensitivity to pain described in the literature, but there is no standard treatment [2]. Patients with CIPA can live a fairly normal life [4, 7, 10].
What is the disease CIPA?
Congenital insensitivity to pain and anhidrosis (CIPA) is HSAN type IV. CIPA is a rare disease with an autosomal recessive inheritance. Recurrent episodes of fever, no sweating, insensitivity to pain, and self-injury are symptoms of CIPA. In addition, most patients suffering from CIPA experience mental ation [1].
What does CIPA mean?
Congenital insensitivity to pain with anhidrosis. Its characterized by the inability to feel physical pain and the inability to sweat from birth. People with CIPA often have recurrent fevers, an inability to perceive temperature extremes, developmental delays, behavioral problems, and hypotonia. Congenital Insensitivity to Pain: Diagnosis, Treatment, and More webmd.com children what-is-congenital- webmd.com children what-is-congenital-
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