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As a reagent in organic chemistry, DBU is used as a catalyst, a complexing ligand, and a non-nucleophilic base. It is also used as a curing agent for epoxy resins. It is also used as a catalyst in the production of polyurethanes.
May be harmful by inhalation, ingestion, or skin absorption. May cause damage to {liver, spleen, oral} through prolonged or repeated exposure. May cause eye, skin, or respiratory system irritation. Suspected of damaging fertility or the unborn child.
DBU is a popular amidine base because it can be deemed to be of lower nucleophilicity than cheaper amidines e.g. formamidine. It has been sometimes erroneously labelled as "non-nucleophilic" but seeing as it reacts with carbon dioxide and sulfonyl halides and anhydrides, this cannot be supported.
Harmful in contact with skin and if swallowed. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. The material can produce severe chemical burns within the oral cavity and gastrointestinal tract following ingestion.
Trimethylolpropane is a primary alcohol.
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The DBU plays a triple role as base, nucleophile and ligand in the synthesis of internal alkynes from 1,1-dibromoalkenes at ambient temperature.
DBU (1,8-diazabicyclo[5.4. 0]undec-7-ene) is a strong tertiary amine base (pH 12.8) with a double heterocyclic structure, which has been widely used in organic synthesis.
DBU is considered to be a non-nucleophilic base. DBU can serve as a base, catalyst, or complexing ligand in a wide variety of reactions.
0]non-5-ene (DBN) is a chemical compound with the formula C7H12N2. It is an amidine base used in organic synthesis. A related compound with related functions is 1,8-diazabicyclo[5.4.
The DBU plays a triple role as base, nucleophile and ligand in the synthesis of internal alkynes from 1,1-dibromoalkenes at ambient temperature.

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