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Is kappa light chain cancerous?

Light chain myeloma can be classified as lambda or kappa light chain myeloma, depending on which type the cancerous cells produce. These light chains can build up in the kidneys, nerves, or other organs and cause serious complications.

How high can kappa light chains go?

Serum FLC assay The free-kappa light chain values ranged from 0.1 mg/L to 1210 mg/L (median, 20 mg/L), whereas the free-lambda light chain values ranged from 0.1 mg/L to 10 100 mg/L (median, 20 mg/L).

What are free light chains in the blood?

Plasma cells normally produce some excess light chains that do not combine with heavy chains and instead enter the bloodstream. Free light chains (FLC) or serum free light chains (SFLC) refer to those that are not part of whole (intact) immunoglobulins and are present in the blood.

What causes elevated free light chains?

The more free light chains in your blood, the more plasma cells you have. This may mean there is a problem with the plasma cells. This test is used to help diagnose a type of cancer called multiple myeloma. It may also be used to diagnose other conditions affecting the cells in your bone marrow.

What does it mean when the kappa light chain is high?

A kappa free light chain test is a quick blood test that measures certain proteins in your blood. High levels of these proteins may mean you have a plasma cell disorder.

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