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Sickle cell anemia occurs when a person inherits two sickle cell genes, one from each parent. If both parents have sickle cell trait, there is a 25% (1 in 4) chance with EACH pregnancy that the baby will have sickle cell anemia. A child with sickle cell anemia appears normal at birth.
- The genotype of the roan cattle is "Ww," the red one is "WW" and the white one is "ww." A hybrid between a roan bull and a roan cow produces red, roan and white phenotypes at 1:2:1 ratios, respectively. - The cross between roan bull (Ww) and red cow (WW) develops roan and red phenotypes at a 1:1 ratio.... RRRRRRR1 more row
A very very very very very common phenotype used in questions about codominance is roan fur in cattle. Cattle can be red (RR = all red hairs), white (WW = all white hairs), or roan (RW = red & white hairs together). A good example of codominance.
In order for Michaela and Jerome to have a child with sickle cell anemia, they must both be heterozygous, which would confer a 1/4 chance of having a child with the disease.
If both parents have sickle cell trait (HbAS) there is a one in four (25%) chance that any given child could be born with sickle cell anaemia. There is also a one in four chance that any given child could be completely unaffected. There is a one in two (50%) chance that any given child will get the sickle cell trait.

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In cattle, roan coat color (mixed red and white hairs) occurs in the heterozygous (Rr) offspring of red (RR) and white (rr) homozygotes. When two roan cattle are crossed, the phenotypes of the progeny are found to be in the ratio of 1 red : 2 roan : 1 white.
Two pea plants, both heterozygous for flower color, are crossed. The offspring will show the dominant purple coloration in a 3:1 ratio. Or, about 75% of the offspring will be purple.
A Punnet square reveals that 75% of the generation will be purple (PP or Pp) and 25% will be white (pp). Of the three purple flowers in the punnett square, two of them are heterozygous for color (Pp). The other flower is homozygous for the purple allele (PP).
Sickle cell disease is an inherited blood disorder. Children can: inherit only one sickle cell gene from a parent.
If both parents have SCT, there is a 50% (or 1 in 2) chance that any child of theirs also will have SCT, if the child inherits the sickle cell gene from one of the parents. Such children will not have symptoms of SCD, but they can pass SCT on to their children.

genetics practice 2 beyond the basics answer key