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The genotype for a specified gene in a mouse can be homozygous, heterozygous, wild type, and sometimes hemizygous (such as X-linked genes or transgenes). You may even have multiple genes with multiple genotypes in one mouse. The genotype of your mouse determines the phenotype.
Definition. A genotype is a scoring of the type of variant present at a given location (i.e., a locus) in the genome. It can be represented by symbols. For example, BB, Bb, bb could be used to represent a given variant in a gene.
Mice are the most commonly used animal model for studying human disease, and for many good reasons: Mice are biologically very similar to humans and get many of the same diseases, for the same genetic reasons. Mice can be genetically manipulated to mimic virtually any human disease or condition.
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The genotype for a specified gene in a mouse can be homozygous, heterozygous, wild type, and sometimes hemizygous (such as X-linked genes or transgenes).
The black-fur parent has the genotype FF Ee, and the white-fur parent has the genotype ff Ee.
The mouse genome closely mirrors that of the human. It contains 2.6 billion nucleotides assembled in 21 chromosomes (1\u201319 plus the X and Y sex chromosomes). Analysis of the current reference genome release (Build 37) shows 28,947 genes with nucleotide sequence data and 25,106 genes with protein sequence data.
Almost all of the genes in mice share functions with the genes in humans. That means we develop in the same way from egg and sperm, and have the same kinds of organs (heart, brain, lungs, kidneys, etc.) as well as similar circulatory, reproductive, digestive, hormonal and nervous systems.
A description of the pair of alleles in our DNA is called the genotype. Since there are three different alleles, there are a total of six different genotypes at the human ABO genetic locus. The different possible genotypes are AA, AO, BB, BO, AB, and OO.

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