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There could be a variety of potential reasons for an increased risk. In some children, antidepressants may also trigger anxiety, agitation, hostility, restlessness or impulsive behavior. These effects may indicate that the child's depression is getting worse or that the child is starting to develop suicidal thoughts.
Driving and operating machinery. Some antidepressants can cause dizziness, drowsiness and blurred vision, particularly when you first start taking them. If you do experience these problems, you should not drive or use tools and machinery.
Two non-SSRI antidepressants are approved by the FDA for treating generalized anxiety disorder in children (ages 7 and older): One SNRI, (), and one atypical antidepressant, (clomipramine).
Antidepressants Impact the Brain Specifically, changes in the functional structure of the brain have been observed after a single dose of SSRI medication. Therefore, this is significant because the teenage brain is still developing. In fact, the brain does not fully mature until a person's mid-20s.
The United States Food and Drug Administration issued a Black Box warning in October 2004 after placebo-controlled trials of antidepressant medications found an increased risk of suicidal thoughts and behaviors among children and adolescents taking antidepressant medications relative to placebo.
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Selective serotonin reuptake inhibitors (SSRIs) are the most commonly used class of antidepressants in both children and adults.
Monitor for adverse effects (e.g. hypotension, suicidal thoughts, cardiac arrhythmias, etc). Evaluate patient understanding on drug therapy by asking the patient to name the drug, its indication, and adverse effects to watch for. Monitor patient compliance to drug therapy.
There could be a variety of potential reasons for an increased risk. In some children, antidepressants may also trigger anxiety, agitation, hostility, restlessness or impulsive behavior. These effects may indicate that the child's depression is getting worse or that the child is starting to develop suicidal thoughts.
The use of antidepressants is not usually recommended in children and young people under the age of 18. This is because there is some evidence that, in rare cases, they can trigger thoughts about suicide and acts of self-harm in this age group.
SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons.

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