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In people, the incubation period (the time between initial contact with the virus and onset of the disease) generally ranges from two to eight weeks. In rare cases, it can vary from 10 days to 2 years. The incubation period is shorter in children and in people exposed to a large dose of the rabies virus.
Tests are performed on samples of saliva, serum, spinal fluid, and skin biopsies of hair follicles at the nape of the neck. Saliva can be tested by virus isolation or reverse transcription followed by polymerase chain reaction (RT-PCR). Serum and spinal fluid are tested for antibodies to rabies virus.
The primary vaccines required for pets in Massachusetts include a rabies shot, which is given between three and six months of age, as well as throughout the animal's lifetime to protect their immunity.
If you are unsure, seek medical advice to be safe.) Remember that rabies is a medical urgency but not an emergency. Decisions should not be delayed. See your doctor for attention for any trauma due to an animal attack before considering the need for rabies vaccination.
Five general stages of rabies are recognized in humans: incubation, prodrome, acute neurologic period, coma, and death (or, very rarely, recovery) (Fig.
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You must get your dog, cat or ferret vaccinated against rabies before it can travel.
The state of Massachusetts requires that all cats are vaccinated against the rabies virus by a licensed veterinarian. Rabies is a virus of the central nervous system and is almost always fatal.
Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-stranded RNA genomes. Within this group, viruses with a distinct \u201cbullet\u201d shape are classified in the Rhabdoviridae family, which includes at least three genera of animal viruses, Lyssavirus, Ephemerovirus, and Vesiculovirus.
After an average of 30 to 50 days (as short as 14 days or longer than a year) from exposure to a rabid animal, a person develops an illness that may include fever, sore throat, stiff muscles, headache, tiredness, restlessness, nausea, and itching or tingling at the site of the bite.
The median risk of rabies transmission without rabies PEP for a bite exposure by a skunk, bat, cat, and dog was estimated to be 0.05, 0.001, 0.001, and 0.00001, respectively.

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