5a. Notice of Possible Exposure to Rabies - Mass.Gov - mass 2025

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Rabies PEP consists of wound washing, a dose of human rabies immune globulin (HRIG) and rabies vaccine given at the time of your first medical visit, and a dose of vaccine given again on days 3, 7, and 14 after the first dose.
The WHO rabies exposure categories are: Category I touching or feeding animals, animal licks on intact skin (no exposure); Category II nibbling of uncovered skin, minor scratches or abrasions without bleeding (exposure); Category III single or multiple transdermal bites or scratches, contamination of mucous membrane or
Massachusetts State Law requires a 10-Day rabies quarantine for any dog, cat, or other domesticated mammal which bites or scratches a human or other animal, regardless of vaccination status.
Sometimes it is hard to be sure if there is a break in the skin. In that case, it is safer to be vaccinated. Even if you have been bitten a few days, or weeks ago, It is never too late to start. Rabies virus can incubate for several years before it causes symptoms.
2. Non-Bite: The contamination of open wounds, abrasions, mucous membranes, or scratches with saliva or other potentially infectious material (neural tissue, cerebrospinal fluid, salivary gland tissue) constitutes an exposure.
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Open wound exposure: Introduction of saliva or other potentially infectious material (cerebrospinal fluid, spinal cord, or brain tissue) from a rabid or potentially rabid animal into an open wound (e.g., broken skin that bled within the past 24 hours).

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