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The recommended daily intake (RDI) of vitamin B12 is 6 micrograms per day. Deficiency is common, especially in people who follow a vegetarian or vegan diet. In fact, it's thought that up to 90% of people following these diets have a deficiency ( 2 , 3 ). This is because B12 is only found naturally in animal foods.
How much vitamin B-12 should you take? CategoryVitamin B-12: Recommended Dietary Allowance (RDA) in micrograms (mcg) For children under age 1, only an adequate intake (AI) is available9-13 years1.8 mcg/day14 years and up2.4 mcg/dayPregnant women2.6 mcg/dayBreastfeeding women2.8 mcg/day4 more rows • Jan 24, 2021
Safety and side effects Headache. Nausea and vomiting. Diarrhea. Fatigue or weakness. Tingling sensation in hands and feet.
FDA regulates both finished dietary supplement products and dietary ingredients. FDA regulates dietary supplements under a different set of regulations than those covering "conventional" foods and drug products. Under the Dietary Supplement Health and Education Act of 1994 (DSHEA):
Taking B12 supplements can be an effective way to treat B12 deficiencies and isn't necessarily inferior to B12 shots. If you're deficient, your doc may recommend you take about 1,000 to 2,000 mcg of vitamin B12.
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There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.
Why doesn't the Food and Drug Administration (FDA) regulate the safety and sale of nutritional supplements? Because they're classified as food products, not medicines, so they aren't regulated by the strict standards governing the sale of prescription and over-the-counter drugs.
FDA has not approved these products and cannot be assured of their safety, effectiveness, or quality.... Product NameSizeVitamin B12 Cyanocobalamin Injection USP 1000 mcg/ml30 ml vialVitamin B12 Cyanocobalamin with MIC Injection USP 1000 mcg/ml10 ml vial20 more rows • 11 Sept 2015
The exact dosage is determined by your doctor depending on your medical condition. Generally, a daily dosage of 1000 micrograms is used to treat a deficiency without any side effects.
Why doesn't the Food and Drug Administration (FDA) regulate the safety and sale of nutritional supplements? Because they're classified as food products, not medicines, so they aren't regulated by the strict standards governing the sale of prescription and over-the-counter drugs.

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