Imaging Melanoma: 2025

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Elective Lymph Node Dissection. Sentinel Lymph Node Biopsy. Complete Chemistry Panel. Lactate Dehydrogenase Assay. Chest Radiography. Magnetic Resonance Imaging. Computed Tomography. Positron Emission Tomography. PET/CT is currently the most sensitive tool for the diagnosis of metastatic disease.
Computed tomography (CT) scan This test can show if any lymph nodes are enlarged or if organs such as the lungs or liver have suspicious spots, which might be from the spread of melanoma. CT-guided needle biopsy: CT scans can also be used to help guide a biopsy needle into a suspicious area within the body.
Since a biopsy is the gold standard for making a melanoma diagnosis, your doctor may suggest a biopsy regardless of your non-invasive testing result.
Unlike a regular x-ray, CT scans can show the detail in soft tissues (such as internal organs). This test can show if any lymph nodes are enlarged or if organs such as the lungs or liver have suspicious spots, which might be from the spread of melanoma.
A CT scan creates a 3-dimensional picture of the inside of the body using x-rays taken from different angles. A computer combines these images into a detailed, cross-sectional view that shows any abnormalities or tumors. If melanoma has spread, a CT scan can be used to measure the tumors size.
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If there is concern that the melanoma has spread, imaging tests might be used to look for signs of cancer in other areas of the body. Tests might include X-ray, MRI , CT and positron emission tomography, which is also called a PET scan.
Positron Emission Tomography (PET) scan: A PET scan can check for melanoma in lymph nodes and other parts of your body distant from the original melanoma skin spot. Blood work: Blood tests may be used to measure lactate dehydrogenase (LDH) before treatment.

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