Frontotemporal dementia Primary progressive aphasia - 2025

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Primary progressive aphasia is a type of frontotemporal dementia. Frontotemporal dementia is a cluster of conditions that result from the degeneration of the frontal or temporal lobes of the brain. These areas include brain tissue involved in speech and language.
The other main type of FTD is called primary progressive aphasia (PPA). This is when the early symptoms of dementia are dominated by problems using language. Problems with other aspects of thinking, mood and behaviour tend to be less noticeable at first. However, as the disease progresses, they may become more severe.
For about 2 decades, cases of PPA were generally categorized as semantic dementia or progressive nonfluent aphasia, or in some studies as fluent vs nonfluent. However, there were a number of PPA cases that did not seem to fit a binary classification,10 and a third clinical variant was empirically described and
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