Research protocol bapplicationb with the Institutional Review Board (Sam H 2025

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The main role of the Institutional Review Board (IRB) in the research process is to protect the rights, dignity, and welfare of human research participants. This is crucial because research involving humans can pose ethical challenges and potential risks to individuals.
It is responsible for the establishment and implementation of initial and ongoing training programs in regard to federal regulations and institutional policies on the protection of human subjects. Part of this responsibility is to maintain up-to-date and accurate records of training by individuals.
When reviewing research, Institutional Review Board (IRB) members are guided by three ethical principles that are fundamental to human participant protection: respect for persons, beneficence, and justice.
The IRB is concerned with protecting the welfare, rights, and privacy of human subjects. The IRB has the authority to approve, exempt, disapprove, monitor, and require modifications in all research activities that fall within its jurisdiction as specified by both the federal regulations and institutional policy.
Under the Common Rule, IRBs must have at least five members and include at least one scientist, one non-scientist, and one member who is not otherwise affiliated with the institution and who is not part of the immediate family of a person who is affiliated with the institution( 46.107(d)).
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Institutional Review Board is a committee established to review and approve research involving human subjects. The purpose of the IRB is to ensure that all human subject research be conducted in ance with all federal, institutional, and ethical guidelines.
Activities that meet the federal regulatory definition of research with a human subject require IRB review. Secondary Research involves re-using identifiable information and identifiable biospecimens that are collected for some other primary or initial activity.

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