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Hazardous Substance Safety Appendix for IACUC Protocols

Hazardous Substance Safety Appendix for IACUC Protocols 2025

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The document outlines the procedures and requirements for completing the Hazardous Substance Safety Appendix for animal research protocols involving hazardous substances. It details the submission process, review timeline, and necessary information regarding hazardous substances, including their identification, preparation, administration, animal care, waste disposal, and safety measures. The Principal Investigator (PI) is responsible for ensuring compliance with safety protocols and training staff on handling hazardous materials.

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What are some elements of the protocol that the IACUC will review?

Studies that involve unobtrusive observation of animals in their natural habitats do not require IACUC oversight. If the study has a potential to cause harm or materially alter the behavior of the animals, then IACUC oversight is required.

What is the IACUC animal protocol?

What types of animals require an IACUC protocol? All vertebrate animals (animals with a backbone) require an IACUC protocol.

What requires IACUC approval?

Required categories of membership include: Veterinarian. The PHS Policy and AWRs mandate the appointment of a veterinarian with direct or delegated program responsibility to the IACUC. Chair. Vice Chair. Nonaffiliated. Scientist. Nonscientist. Alternate Members. Ex Officio.

What is the IACUC and what does it do?

The Institutional Animal Care and Use Committee (IACUC) is established by federal mandate at institutions that use live, vertebrate animals for research, teaching, and testing activities. The IACUC oversees and evaluates all aspects of the institutions animal care and use program.

What is the IACUC protocol?

An institutional animal care and use committee (IACUC) is required by federal regulations for most institutions that use animals in research, teaching, and testing. The IACUC has a key oversight role, including the review and approval of animal use activities, and inspection of animal facilities.

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