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Of Slime Mold Aggregation Viewed as an Instability

Of Slime Mold Aggregation Viewed as an Instability 2025

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The document presents a mathematical analysis of the aggregation process in slime molds, specifically focusing on the chemotactic interaction mediated by acrasin. It describes how aggregation can be viewed as an instability in a uniform distribution of amoebae, triggered by changes in cell properties. The authors develop equations to model the concentrations of amoebae, acrasin, and acrasinase, and analyze conditions under which aggregation occurs. The findings suggest that increases in sensitivity to acrasin gradients or production rates can lead to instability and subsequent aggregation, supported by experimental observations.

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What is an aggregation called plasmodium?

An aggregate of slime moulds which may grow and spread over several feet is called. Plasmodium.

What is the aggregation of slime molds?

Slime moulds are saprophytes that lack chlorophyll. During favourable conditions, they form aggregates called plasmodium that can spread and grow widely. The plasmodium forms spores during unfavourable conditions. The spores have true cell walls and are extremely resistant to adverse conditions.

What factors initiate aggregation in the cellular slime molds?

As a wave of cAMP passes an amoeba, it stimulates cAMP synthesis by the cell, thereby regenerating the signal, and it stimulates chemotactic movement of the cell in the direction from which the wave came, thereby causing the amoebae to aggregate at the centre of the pattern.

What is the chemical signal for slime mold amoebas to aggregate?

The chemicals that aggregate cellular slime molds are small molecules called acrasins; motion towards a chemical signal is called chemotaxis. The first acrasin to be discovered was cyclic adenosine monophosphate (cyclic AMP), a common cell signaling molecule, in Dictyostelium discoideum.

What is the significance of slime molds in the ecosystem?

They play an important role as decomposers and recyclers of nutrients in the food web. Their diet consists of the bacteria which feed on decomposing plant matter. In turn, slime molds may be consumed by nematodes, beetles, and other larger life forms.

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