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Incidence of Eosinophilic Esophagitis in Marshfield Epidemiological

Incidence of Eosinophilic Esophagitis in Marshfield Epidemiological 2025

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The document presents a study conducted by Rajesh B Kethireddy, MD, aimed at estimating the incidence of Eosinophilic Esophagitis (EE) in the Marshfield Epidemiological Study Area (MESA) and describing the demographic features of diagnosed patients. The research highlights the increasing prevalence of EE, its association with atopic dermatitis, and outlines the methodology for identifying cases through retrospective cohort analysis. The study emphasizes the significance of understanding EE's incidence rates over different time periods and its implications for patient morbidity.

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What foods should you avoid if you have eosinophilic esophagitis?

Excluding certain foods from the diet has been a cornerstone of EoE treatment. During the early 2000s, researchers found that eliminating six common food triggers of esophageal injurymilk, egg, wheat, soy, fish and nutssubstantially reduced signs and symptoms of EoE.

What is the gold standard for eosinophilic esophagitis?

Currently, the gold standard for diagnosing EoE is endoscopic biopsy.

What is the 4 14 4 rule for EoE?

The attendees of the consensus meeting, which was attended by 82% of the invited endoscopy leaders, concluded that they would obtain esophageal biopsies using the 4-14-4 rule (4 biopsies from 14 cm and 4 cm above the gastroesophageal junction) and that pathologists would report when eosinophilia especially 15

What is the biggest trigger for EoE?

Overall in the various studies throughout the world, milk is the most common allergen causing disease in about 2/3 of patients followed by egg and wheat in another of the patients. Although milk is the most common antigenic trigger for EoE, EoE is also triggered in many patients by other foods.

What is the incidence of eosinophilic esophagitis?

EoE can be seen in 27% of patients undergoing endoscopy for any reason, and 1223% undergoing endoscopy for dysphagia. The incidence of EoE is approximately 1/10,000 new cases per year, and the rise in incidence is outpacing increases in recognition and endoscopy volume.

How many people in the US have eosinophilic esophagitis?

Affected populations An epidemiologic study published in 2025 found that the prevalence of EoE was 142.5/100,000 and estimated 472,380 total cases in U.S, so EoE is no longer considered rare in the U.S. EoE is not considered a rare condition in Europe.

What autoimmune diseases are associated with EoE?

Its pathogenesis is incompletely understood; however, an association with autoimmune diseases, including Hashimotos thyroiditis, celiac disease, Crohns disease, ulcerative colitis (UC), and rheumatoid arthritis, was identified in a Utah population-based cohort study (2).