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Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness

Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness 2025

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The document investigates the relationship between elevated aortic pulse wave velocity (aPWV), a marker of arterial stiffness, and cardiovascular events in well-functioning older adults. It analyzes data from 2,488 participants in the Health ABC study, revealing that higher aPWV is significantly associated with increased total mortality, cardiovascular mortality, coronary heart disease (CHD), and stroke over an average follow-up of 4.6 years. The findings suggest that aPWV can serve as an important predictor of cardiovascular health in older populations.

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What does high aortic velocity mean?

An increased aortic pulse wave velocity (PWV), a marker of arterial stiffness, is associated with poor prognosis in various diseases. In patients with heart failure (HF), an increased aortic PWV is associated with low peak exercise oxygen consumption, which is a strong risk factor of adverse clinical outcomes.

What is the normal velocity of the aorta?

The ascending aorta has the highest average peak velocities of the major vessels; typical values are 150-175 cm/sec. Flow in the distal aorta and iliac vessels slows to the 100-150 range, whereas peak velocities in the proximal carotid, brachial, and superficial femoral arteries are about 80-110 cm/sec.

What does aortic velocity mean?

Aortic velocity (the speed at which the blood flows) quickly peaks during the first third of the heart contraction (systole) and then falls to your normal resting pressure during the rest of the systole.

Is high velocity on an echocardiogram bad?

Increased Aortic Pulse Wave Velocity as Measured by Echocardiography Is Strongly Associated with Poor Prognosis in Patients with Heart Failure.

What does arterial stiffness indicate?

Pulse wave velocity (PWV) is a biomarker directly related to vessel stiffness that has the potential to provide information on early atheroscl disease burden. A number of clinical methods are available for evaluating global PWV, including applanation tonometry and ultrasound.

How does pulse wave velocity relate to arterial stiffness?

This is the distance traveled by blood flow divided by the time it takes to travel that distance (in meters/second). It is measured non-invasively and is the gold standard for assessment of aortic stiffness. The lower the PWV the better, as this means the arteries have maintained their elasticity and are distensible.

What does high blood velocity mean?

Blood Velocity At rest, the peak velocity in the aorta is about 1 m/sec and this may increase to more than 3 m/sec during exercise, when cardiac output is increased. Similarly, blood velocity increases at a site of pathologic narrowing (e.g., aortic coarctation, aortic valve stenosis).

Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness 2025

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What does high aortic velocity mean?

What is the normal velocity of the aorta?

What does aortic velocity mean?

Is high velocity on an echocardiogram bad?

What does arterial stiffness indicate?

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How does pulse wave velocity relate to arterial stiffness?

What does high blood velocity mean?

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Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness 2025

Here's how it works

How to rapidly redact Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness online

Complete this form in 5 minutes or less

Got questions?

What does high aortic velocity mean?

What is the normal velocity of the aorta?

What does aortic velocity mean?

Is high velocity on an echocardiogram bad?

What does arterial stiffness indicate?

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People also ask

How does pulse wave velocity relate to arterial stiffness?

What does high blood velocity mean?

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