Oscillatory patterns in temporal lobe reveal context reinstatement 2025

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The medial temporal lobe is primarily involved in retrieval from off-line memory and triggers the reactivation by associating a whole set of features and episodes during encoding of the information. The prefrontal cortex is involved in retrieval from both on-line and off-line memory.
Most available evidence suggests that the functions of memory are carried out by the hippocampus and other related structures in the temporal lobe.
A curved seahorse-shaped organ on the underside of each temporal lobe, the hippocampus is part of a larger structure called the hippocampal formation. It supports memory, learning, navigation and perception of space. It receives information from the cerebral cortex and may play a role in Alzheimers disease.
The medial temporal lobe (MTL) includes the hippocampus, amygdala and parahippocampal regions, and is crucial for episodic and spatial memory. MTL memory function consists of distinct processes such as encoding, consolidation and retrieval.
They are most commonly associated with processing auditory information and with the encoding of memory. The temporal lobes are also believed to play an important role in processing affect/emotions, language, and certain aspects of visual perception.