Typhoid and Paratyphoid Fever Case Report - California - cdph ca 2025

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In the U.S., about 400 cases occur each year, 75% of which are acquired while traveling internationally. Before the antibiotic era, the case fatality rate of typhoid fever was 1020%. Today, with prompt treatment, it is less than 1%, but 35% of people who are infected develop a chronic infection in the gall bladder.
The California Department of Public Health (CDPH) receives reports of approximately 75 cases of typhoid fever each year in California.
A diagnosis of typhoid fever can usually be confirmed by analysing samples of blood, poo, or pee. These will be examined under a microscope for the Salmonella typhi bacteria that cause the condition.
The chances of getting typhoid fever or paratyphoid fever in the United States are very low. The chances increase for people in the United States who: Travel to countries in Africa, Asia, or Latin America where the diseases are common. Visit rural areas of those countries.
Human cases of flea-borne typhus are reported worldwide, but mainly in tropical and coastal areas. In the United States, most cases occur in Texas, California, and Hawaii, with an average of about 300 cases every year.
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Most cases of Valley fever in California are reported from the Central Valley and Central Coast regions.
Epidemiology. An estimated 1121 million cases of typhoid fever and 5 million cases of paratyphoid fever occur worldwide each year, causing an estimated 135,000230,000 deaths.

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