ContributorsClinical Genomics: Practical Applications in Adult 2025

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Genomics is now being used in a wide variety of fields, such as metagenomics, pharmacogenomics, and mitochondrial genomics. The most commonly known application of genomics is to understand and find cures for diseases.
Clinical scientists are responsible for writing a report that goes back to the clinician managing a patient and their family, informing them of the results of genomic testing. They tend to specialise in either rare disease or cancer.
Genomic technologies are increasingly being used to understand the contribution of both rare and common genetic factors to the development of common diseases, such as high blood pressure, diabetes and cancer.
In addition to rare disease and familial cancer applications, genomic data can be used to generate a personalized risk assessment for common diseases as well as aid in predicting disease risk in healthy individuals.
Genome-driven diagnoses may in the short-term guide clinical treatment or management of phenotypes associated with rare disease, while at the same time potentially yielding beneficial medical information that will aid a patient throughout their lifetime.

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Mayo Clinic Department of Clinical Genomics uses genomic testing to personalize care. Our experts develop knowledge about a persons DNA to help predict, prevent, diagnose and treat disease. Our specialized approach allows us to individualize care at the deepest levels.
Sequencing the genomes of microorganisms which cause human infection can identify the exact organism causing symptoms, help to trace the cause of infectious outbreaks, and give information as to which antibiotics are most likely to be effective in treatment.

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